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Poolse asbestwerkers hebben groter risico op mesothelioom en longkanker

12-07-2006 00:00

Sinds 1980 zijn de sterftecijfers van 4187 ex-werknemers van een Poolse fabriek van asbestproducten vergeleken met de Poolse bevolking in het algemeen. Zowel longkanker als mesothelioom kwamen bij de asbestwerkers vaker voor. Bij vrouwen was het verschil nog groter, volgens de onderzoekers een aanwijzing dat vrouwen wellicht gevoeliger voor asbest zijn dan mannen. Er werd geen direct verband gevonden tussen het hebben van asbestose (een stoflongziekte) en een verhoogd risico op longkanker. Bron: Wilczynska U. et al., (2005) Mortality from malignant neoplasms among workers of an asbestos processing plant in Poland: results of prolonged observation. International Journal of Occupational Medicine and Environmental Health 18(4):313-26.
Wilczynska U, Szymczak W, Szeszenia-Dabrowska N., (2005). Mortality from malignant neoplasms among workers of an asbestos processing plant in Poland: results of prolonged observation. International Journal of Occupational Medicine and Environmental Health 18(4):313-26.

ABSTRACT


OBJECTIVES: The study on mortality from cancer among workers of an asbestos plant manufacturing asbestos yarn, cloth, cords, packings, stuffing, brake linings and asbestos-rubber sheets was launched in the 1980s. The present paper discusses the results of further tracing of asbestos workers of the same plant. MATERIALS AND METHODS: The study cohort covered 4497 workers employed at the asbestos plant in 1945-1980. The follow-up of the cohort continued until 31 December 1999. Deaths by causes were analyzed using standardized mortality ratio (SMR) calculated by the person-years method. The mortality pattern of the general population of Poland was used as reference. RESULTS: The availability of the cohort was 93.1% (2805 men and 1382 women were traced). Mortality from malignant neoplasms in total (281 deaths among men, SMR = 118, 95%CI: 105-133 and 135 deaths among women, SMR = 159, 95%CI: 133-188) as well as that from lung cancer (102 deaths among men, SMR = 126, 95%CI: 103-153 and 18 deaths among women, SMR = 259, 95%CI: 153-409) were significantly higher than in the general population. Unlike earlier stages of analysis, the present study revealed an increased risk of pleural mesothelioma (2 deaths among men, SMR = 510, 95%CI: 62-1842 and 3 deaths among women, SMR = 2033, 95%CI: 419-5941). Mortality analysis among workers with asbestosis and in those without diagnosed asbestosis, did not reveal direct association between the risk of asbestos-induced lung cancer and previously diagnosed asbestosis. CONCLUSIONS: The prolonged cohort tracing showed an increased risk of asbestos-related cancers. It concerned mainly workers hired by the plant between 1945-1955, when the working condition were most strenuous.