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Epidemiologisch nieuws

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VK: meer mesothelioom bij personeel electriciteitscentrale

23-02-2006 00:00

Nichols en Sorahan vonden een hoger dan gemiddelde incidentie van mesothelioom bij mensen die in de periode tussen 1973 en 1982 minimaal zes maanden bij een elektrische centrale van de voormalige 'Central Electricity Generating Board of England and Wales' hadden gewerkt. Bron: Nichols L & Sorahan T. (2005). Mortality of UK electricity generation and transmission workers, 1973-2002. Occupational Medicine Oct.55(7):541-8.
Nichols L & Sorahan T. (2005). Mortality of UK electricity generation and transmission workers, 1973-2002. Occupational Medicine Oct.55(7):541-8.

OBJECTIVE:
To examine mortality from cancer and non-malignant causes among a large cohort of UK electricity generation and transmission workers.

METHODS: The mortality experienced by a cohort of 83,923 employees of the former Central Electricity Generating Board of England and Wales was investigated for the period 1973-2002. All employees had worked for at least 6 months with some employment between 1973 and 1982. Standardized mortality ratios (SMRs) were used to assess mortality in the total cohort and in three sub-cohorts: power station workers, substation and transmission workers and workers at non-operational locations. These classifications were based on the place of work of the first known job.

RESULTS: Overall mortality was significantly below that expected, based on national rates [males: observed (Obs) 18,773, expected (Exp) 22,497.9, SMR 83. females: Obs 1122, Exp 1424.9, SMR 79]. Statistically significant deficits of deaths were also found for most of the major disease groupings. However, significant excesses of deaths were found in male power station workers for cancer of the pleura (Obs 129, Exp 30.3, SMR 426) and in male workers from non-operational locations for cancer of the brain (Obs 55, Exp 36.0, SMR 153). There was also a non-significant excess of deaths from cancer of the breast in male power station workers (Obs 10, Exp 5.3, SMR 190).

CONCLUSIONS: Mortality was exceptionally low for most causes of death but late health effects from earlier asbestos exposure were still in evidence.